Drug index search
| Drug Name | Synonyms | Target |
|---|---|---|
| Sunitinib | Sutent, Sunitinib Malate, SU-11248 | PDGFR, KIT, VEGFR, FLT3, RET, CSF1R |
| PHA-665752 | PHA665752, PHA 665752 | MET |
| Cyclopamine | SMO | |
| AZ628 | AZ-628, AZ 628 | BRAF |
| Imatinib | Gleevec, STI-571 | ABL, KIT, PDGFR |
| NVP-TAE684 | NVP-TAE 684, TAE684, TAE-684 | ALK |
| Saracatinib | AZD0530, AZD-0530, AZ-10353926 | ABL, SRC |
| S-Trityl-L-cysteine | NSC 83265, Tritylcysteine | KIF11 |
| Z-LLNle-CHO | Z-L-Norleucine-CHO, Gamma-Secretase Inhibitor 1 | gamma-secretase |
| GNF-2 | KIN001-013 | BCR-ABL |
| CGP-60474 | KIN001-019, CGP60474, CGP 60474 | CDK1,CDK2,CDK5,CDK7,CDK9, PKC |
| CGP-082996 | CINK4, KIN001-021 | CDK4 |
| A-770041 | KIN001-111 | LCK, FYN |
| WH-4-023 | KIN001-112 | SRC, LCK |
| WZ-1-84 | KIN001-123 | BMX |
| BMS-509744 | KIN001-127, ITK inhibitor | ITK |
| CMK | KIN001-128 | RSK2 |
| Pyrimethamine | Daraprim, Chloridine | Dihydrofolate reductase (DHFR) |
| JW-7-52-1 | MTOR | |
| A-443654 | KIN001-139 | AKT1, AKT2, AKT3 |
| GW843682X | GW843682X (AN-13) | PLK1 |
| Parthenolide | HDAC1 | |
| GSK319347A | KIN001-135, IKK-3 inhibitor | IKK |
| TGX221 | TGX-221, Tgx 221 | PI3Kbeta |
| XMD8-85 | ERK5-IN-1 | ERK5, BET |
| Seliciclib | Roscovitine, CYC-202, AL-39256 | CDK2, CDK7, CDK9 |
| Salubrinal | EIF-2alpha Inhibitor | EIF2A |
| Doxorubicin | Anthracycline | |
| Etoposide | Etopophos, Vepesid, Eposin, VP-16 | TOP2 |
| Mitomycin-C | Mytozytrex, NSC-26980, MMC, Mitosol, Mitozytrex | DNA crosslinker |
| NSC-87877 | NSC 87877 | SHP-1 (PTPN6), SHP-2 (PTPN11) |
| QS11 | 944328-88-5 | ARFGAP1 |
| CP466722 | CP-466722, CP 466722, 1080622-86-1 | ATM |
| Midostaurin | PKC412, benzoylstaurosporine, CGP-41251 | PKC, PPK, FLT1, c-FGR, others |
| Ponatinib | AP24534, AP-24534, KIN001-192, Iclusig | ABL, PDGFRA, VEGFR2, FGFR1, SRC, TIE2, FLT3 |
| JNK-9L | BAZ2A, BAZ2B | |
| PF-562271 | PF-00562271 | FAK, FAK2 |
| HG6-64-1 | KIN001-206 | BRAF |
| JQ12 | HDAC1, HDAC2 | |
| DMOG | Dimethyloxalylglcine | HIF-PH |
| FTI-277 | Farnesyl-transferase (FNTA) | |
| OSU-03012 | AR-12, OSU 03012, OSU03012, PDK1 inhibitor AR-12 | PDK1 (PDPK1) |
| Shikonin | Anchusin | not defined |
| AKT inhibitor VIII | Akti-1/2, KIN001-102 | AKT1, AKT2, AKT3 |
| Embelin | Emberine, Embelic acid | XIAP |
| FH535 | PPARgamma, PPARdelta | |
| PAC-1 | GTPL5238 | Procaspase-3, Procaspase-7 |
| IPA-3 | IPA 3 | PAK1 |
| GSK650394 | GSK-650394, GSK 650394 | SGK2, SGK3 |
| BAY-61-3606 | Syk Inhibitor, BAY-613606 | SYK |
| Thapsigargin | Octanoic acid | SERCA |
| Bexarotene | LG-100069, Targretin, Targret, Targrexin, Targretyn, Bexarotenum | Retinioic X receptor (RXR) agonist |
| LFM-A13 | DDE-28 | BTK |
| GW-2580 | GX2580, CFMS receptor tyrosine kinase inhibitor | CSF1R |
| Phenformin | DBI | Biguanide agent |
| Bryostatin 1 | Bryostatin | PKC |
| Pazopanib | Votrient | CSF1R, KIT, PDGFRA, PDGFRB |
| Dacinostat | NVP-LAQ824, LAQ824 | HDAC1 |
| Epothilone B | Patupilone, EpoB, EPO906, GNF-PF-193 | Microtubule stabiliser |
| Tipifarnib | Zarnestra | Farnesyl-transferase (FNTA) |
| AS601245 | JNK1, JNK2, JNK2 | |
| Ispinesib Mesylate | SB-715992 | KSP |
| TL-2-105 | not defined | |
| AT-7519 | AT7519 | CDK1, CDK2, CDK4, CDK6, CDK9 |
| TAK-715 | KIN001-201, TAK 715 | p38alpha, p38beta |
| BX-912 | PDK1 (PDPK1) | |
| ZSTK474 | KIN001-167, ZSTK-474, ZSTK 474 | PI3K (class 1) |
| AS605240 | KIN001-173, AS-605240 | PI3Kgamma |
| Genentech Cpd 10 | AURKA, AURKB | |
| GSK1070916 | GSK-1070916 | AURKA, AURKC |
| Enzastaurin | LY317615 | PKCB |
| GSK429286A | ROCK1, ROCK2 | |
| FMK | KIN001-242 | RSK |
| QL-XII-47 | IRAK1 | |
| IC-87114 | PI3Kdelta | |
| Idelalisib | CAL-101, Zydelig | PI3Kdelta |
| Cabozantinib | BMS-907351, XL-184, Cometriq | VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, TIE2,AXL |
| WZ3105 | SRC, ROCK2, NTRK2, FLT3, IRAK1, others | |
| XMD14-99 | ALK, CDK7, LTK, others | |
| Quizartinib | AC220, AC 220, AC-220, Asp-2689 | FLT3 |
| CP724714 | CP-724714 | ERBB2 |
| JW-7-24-1 | LCK | |
| NPK76-II-72-1 | PLK3 | |
| STF-62247 | STF62247 | Autophagy inducer |
| NG-25 | TAK1 | |
| TL-1-85 | TAK1, MAP4K2 | |
| FR-180204 | FR 180204, FR180204, ERK Inhibitor II | ERK1, ERK2 |
| ACY-1215 | HDAC6 | |
| Tubastatin A | HDAC1, HDAC6, HDAC8 | |
| Zibotentan | ZD4054, ZD-4054 | Endothelin-1 receptor (EDNRA) |
| NSC-207895 | XI-006, NSC207895 | MDM4 |
| VNLG/124 | HDAC inhibitor XV | HDAC,RAR |
| AR-42 | HDAC-42, AR 42, AR42 | HDAC1 |
| CUDC-101 | CUDC 101 | HDAC1-10, EGFR, ERBB2 |
| Belinostat | PXD101, PXD-101 | HDAC1 |
| CAY10603 | HDAC1, HDAC6 | |
| Linifanib | ABT-869, ABT 869 | VEGFR1, VEGFR2, VEGFR3, CSF1R, FLT3, KIT |
| BIX02189 | BIX 02189 | MEK5, ERK5 |
| Alectinib | CH5424802, CH 542802, Alecensa | ALK |
| Pelitinib | EKB-569, EKB 569 | EGFR |
| Omipalisib | GSK2126458, GSK-2126458, EX-8678, GSK458 | PI3K (class 1), MTORC1, MTORC2 |
| JNJ38877605 | MET | |
| SU11274 | MET | |
| KIN001-236 | HDAC6, HDAC10 | |
| KIN001-244 | PDK1 inhibitor 7 | PDK1 |
| WHI-P97 | AC1L1GQE, KIN001-055 | JAK3 |
| KIN001-042 | GSK3B | |
| KIN001-260 | Bayer IKKb inhibitor, ACHP | CDC7 |
| KIN001-266 | CDC7 | |
| Masitinib | AB1010, Masivet | KIT, PDGFRA, PDGFRB |
| Amuvatinib | MP470, MP 470, MP-470 | KIT, PDGFRA, FLT3 |
| MPS-1-IN-1 | MPS1 | |
| NVP-BHG712 | BHG712 | EPHB4, RAF, SRC, ABL |
| OSI-930 | OSI 930 OSI930 | KIT, VEGFR2 |
| CX-5461 | CX5461, CX 5461 | RNA Polymerase 1 |
| PHA-793887 | PHA793887, PHA 793887 | CDK2, CDK7, CDK5 |
| PI-103 | PI-103, PI103, PI 103 | PI3Kalpha, DAPK3, CLK4, PIM3, HIPK2 |
| PIK-93 | PIK 93, PIK93 | PK3CG |
| SB52334 | SB-52334, SB 52334 | ALK5 |
| TPCA-1 | IKK2 | |
| Fedratinib | TG101348, TG-101348, SAR302503, SAR-302503 | JAK2 |
| Y-39983 | ROCK | |
| YM201636 | YM-201636, YM 201636 | PIKFYVE |
| Tivozanib | AV-951, AV 951, KRN-951, KIL8951, ASP-4130 | VEGFR1, VEGFR2, VEGFR3, PDGFR, KIT |
| WYE-125132 | mTOR | |
| GSK690693 | GSK 690693, GSK-690693 | AKT1, AKT2, AKT3 |
| SNX-2112 | SNX 2112 | HSP90 |
| QL-XI-92 | DDR1 | |
| XMD13-2 | MRCKB | |
| QL-X-138 | BTK | |
| XMD15-27 | CAMK2 | |
| T0901317 | TO-901317, TO901317 | LXR, FXR |
| Selisistat | EX-527, EX 527 | SIRT1 |
| Tenovin-6 | SIRT | |
| THZ-2-49 | CDK9 | |
| KIN001-270 | CDK9 inhibitor, CDK9-IN-1 | CDK9 |
| THZ-2-102-1 | CDK7 | |
| AT7867 | AKT | |
| CI-1033 | EGFR, ERBB2, ERBB4 | |
| PF-00299804 | EGFR, ERBB2, ERBB4 | |
| TWS119 | GSK3 | |
| Torin 2 | mTOR | |
| Pilaralisib | XL-147 | PI3K |
| GSK1059615 | PI3K | |
| Voxtalisib | XL-765, SAR245409 | PI3K (class 1), DNAPK, MTOR |
| Brivanib | BMS-540215 | VEGFR, PDGFR |
| BIBF-1120 | VEGFR, PDGFR, FGFR | |
| AST-1306 | EGFR, ERBB4 | |
| Apitolisib | GDC0980 | mTOR, PI3K |
| LIMK1 inhibitor BMS4 | LIMK1 | |
| kb NB 142-70 | PKD | |
| Sphingosine Kinase 1 Inhibitor II | PF-543 | Sphingosine Kinase |
| eEF2K Inhibitor | A-484954 | eEF2K |
| MetAP2 Inhibitor | A832234 | MetAP2 |
| Venotoclax | ABT-199, Veneclexta, GDC-0199 | BCL-2 selective |
| CPI-613 | Metabo, Mitochondria | |
| CAY10566 | Stearoyl-CoA desaturase | |
| Ara-G | 9-??-D-Arabinofuranosyl guanine | Anti-metabolite |
| Pemetrexed | TYMS | |
| Flavopiridol | CDK | |
| C-75 | FAS | |
| CAP-232 | TT-232, TLN-232 | Glycolysis |
| Trichostatin A | HDAC | |
| Panobinostat | Farydak, LBH589 | HDAC |
| IMD-0354 | IKKb | |
| ETP-45835 | MNK1, MNK2 | |
| CD532 | AURKA | |
| NSC319726 | P53 Mut specific | |
| ARRY-520 | KIF11 | |
| A-83-01 | TGFB | |
| LDN-193189 | BMP | |
| FTY-720 | Fingolimod hydrochloride; Gilenya; TDI-132; Imusera; Gilenia | S1P |
| BAM7 | Bax activator | |
| Kobe2602 | RAS effector | |
| RU-SKI 43 | Shh | |
| AICA Ribonucleotide | AICAR, N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide | AMPK agonist |
| CI-1040 | CI 1040, PD-18435, PD-184352, 212631-79-3 | MEK1, MEK2 |
| VX-702 | VX702, VX 702 | p38 |
| CRT0105950 | JNK1, JNK2, JNK3 | |
| CRT0105446 | mTOR, LCK | |
| Cetuximab | Erbitux, IMC-C225, C225, IMC-225, L01XC06 | EGFR |
| FS106 | CHEK1 | |
| Capivasertib | AZ5363 | AKT |
| HG-5-113-01 | AURKA | |
| HG-5-88-01 | TAK1, M4K2 | |
| THZ-1-87 | BTK, BMX | |
| XMD11-50 | LRRK2, ERK5 | |
| XMD11-85h | LRRK2, ERK5 | |
| ZG-10 | JNK1 | |
| XMD8-92 | XMD 8-92 | ERK5 |
| THZ-2-98-01 | IRAK1 | |
| QL-VIII-58 | MTOR, ATR | |
| CRT0160829 | CDC7 | |
| AZ20 | ATR | |
| KU-60019 | ATM | |
| FS112 | KS6B1 (p70S6K) | |
| CCT245232 | HSF1 | |
| CCT245467 | HSF1 | |
| FY026 | [(para-cymene)osmium(N,N-dimethylphenlyazopyridine)(iodide)]hexafluorophophate | |
| FY069 | [(biphenyl)osmium(5-fluoro-phenlyazopyridine)(iodide)]hexafluorophophate | |
| ZL049 | [(diphenyltetramethylcyclopentadienyl)iridium(III)(2-phenylpyridine)(chloride)] | |
| FY012 | ||
| torin2 | MTOR, ATM, ATR, DNAPK | |
| QL-XII-61 | BMX, BTK | |
| HG-6-71-01 | DDR1, DDR2, SRC | |
| I-BET-151 | GSK12100151A | BRD2, BRD3, BRD4 |
| (5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol, LL-Z1640-2 | TAK1 |
| N22899-6-C1 | Peptidyl arginine deaminase (PAD) | |
| N23918-95-7 | JMJ histone demethylase | |
| N24798-49-A1 | JMJ histone demethylase | |
| GSK-J4 | KDM6B | |
| rTRAIL | TRAIL receptor agonist | |
| UNC1215 | UNC-1215 | L3MBTL3 |
| UNC0642 | G9A, GLP | |
| ICL1100013 | N-myristoyltransferase 1/2 | |
| 965-D2 | MKNK1, MKNK2, PIM1, PIM3 | |
| 993-D2 | MKNK1, MKNK2 | |
| BAY ACCi | ACACA | |
| BAY AKT1 | AKT1, AKT2, AKT3 | |
| BAY-HDAC11_1 | HDAC11 | |
| BAY-HDAC11_2 | HDAC11 | |
| BAY-HDAC11_4 | HDAC11 | |
| BAY-MPS1 | MPS1 | |
| BAY-MPS-combo-1 (paclitaxel 5 uM) | TTK and microtubules | |
| BAY-MPS-combo 2 (paclitaxel 1 uM) | TTK and microtubules | |
| ZL109 | DNA damage | |
| AZD3514 | SN1019841295 | AR |
| Bleomycin (10 uM) | dsDNA break induction | |
| AZD6094 | SN1042487586 | MET |
| Dyrk1b_0191 | SN1008982787 | DYRK1B |
| AZD4877 | SN1055467765 | EG5 |
| EphB4_9721 | SN1076287848 | EPHB4 |
| AZD8931 | SN0216062465 | EGFR, ERBB2, ERBB3 |
| FEN1_3940 | SN1106019609 | FEN1 |
| FGFR_0939 | SN1043317881 | FGFR4 |
| FGFR_3831 | SN1037992934 | FGFR1, FGFR2, FGFR3, FGFR4 |
| BPTES | SN1041594574 | GLS |
| AZD7969 | SN1098976045 | GSK3B |
| IAP_7638 | SN1043547481 | IAP |
| IGFR_3801 | SN1056768819 | IGFR1 |
| AZD1480 | SN1044232195 | JAK1, JAK2 |
| JAK1_3715 | SN1042605297 | JAK1 |
| JAK3_7406 | SN1014281280 | JAK3 |
| MCT1_6447 | SN0177231247 | MCT1 |
| MCT4_1422 | SN1043999849 | MCT4 |
| AZD8835 | SN1040214596 | PI3Kalpha, PI3Kdelta |
| PI3Ka_4409 | SN1037097676 | PI3Kalpha, PI3Kdelta |
| PLK_6522 | SN1077317349 | PLK1, PLK2, PLK3 |
| RAF_9304 | SN1034259943 | ARAF, BRAF, CRAF |
| PARP_9495 | SN1024601395 | PARP1, PARP2, PARP7 |
| PARP_0108 | SN1044053371 | PARP1, PARP2, PARP6 |
| PARP_9482 | SN1031920820 | PARP1, PARP2, PARP5a |
| TANK_1366 | SN1032446568 | Tankyrase 1/2 (PARP5a, PARP5b) |
| TTK_3146 | SN1080714093 | TTK |
| PFI-3 | BDF00016096 | PB1, SMARCA4, SMARCA2 |
| I-CBP112 | EP300, CBP | |
| Camptothecin | Camptothecine, (+)-Camptothecin | TOP1 |
| Vinblastine | Velban | Microtubule destabiliser |
| Cisplatin | cis-Diammineplatinum(II) dichloride, Platinol, CIS-DDP | DNA crosslinker |
| Cytarabine | Ara-Cytidine, Arabinosyl Cytosine, U-19920 | Antimetabolite |
| Docetaxel | RP-56976, Taxotere | Microtubule stabiliser |
| Methotrexate | Abitrexate, Amethopterin, Rheumatrex, Trexall, Folex | Antimetabolite |
| Tretinoin | ATRA, Vesanoid, Renova, Atralin, Tretin-X, Avita | Retinoic acid |
| Gefitinib | ZD-1839, Iressa | EGFR |
| Navitoclax | ABT-263, ABT263, ABT 263 | BCL2, BCL-XL, BCL-W |
| Vorinostat | Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683 | HDAC inhibitor Class I, IIa, IIb, IV |
| Nilotinib | Tasigna, AMN 107 | ABL |
| Refametinib | RDEA119, BAY-86-9766, BAY 869766 | MEK1, MEK2 |
| Temsirolimus | CCI-779, Torisel | MTOR |
| Olaparib | AZD2281, KU0059436, Lynparza | PARP1, PARP2 |
| Veliparib | ABT-888, ABT888, ABT 888 | PARP1, PARP2 |
| Bosutinib | SKI-606, Bosulif | SRC, ABL, TEC |
| Lenalidomide | CDC-501, CC-5013, Revlimid | CRBN |
| Axitinib | AG-13736, Inlyta | PDGFR, KIT, VEGFR |
| AZD7762 | AZD-7762, AZD 7762 | CHEK1, CHEK2 |
| GW441756 | GW 441756 | NTRK1 |
| Lestaurtinib | CEP-701, SP-924, SPM-924, A-154475, KT-555 | FLT3, JAK2, NTRK1, NTRK2, NTRK3 |
| SB216763 | SB-216763, SB 216763 | GSK3A, GSK3B |
| Tanespimycin | 17-AAG, BMS-722782 | HSP90 |
| Motesanib | AMG-706, AMG 706, AMG706 | VEGFR, RET, KIT, PDGFR |
| KU-55933 | KU55933 | ATM |
| Elesclomol | STA-4783 | HSP90 |
| Afatinib | BIBW2992, Tovok, Gilotrif | EGFR, ERBB2 |
| Vismodegib | GDC0449, Erivedge | SMO |
| Staurosporine | Broad spectrum kinase inhibitor | |
| PLX-4720 | PLX4720, PLX 4720 | BRAF |
| BX795 | BX-795 | TBK1, PDK1 (PDPK1), IKK, AURKB, AURKC |
| NU7441 | KU-57788, NU-7432, NU-7741 | DNAPK |
| SL0101 | SL-0101, SL 0101-1 | RSK, AURKB, PIM1, PIM3 |
| Doramapimod | BIRB-796, BIRB 796 | p38, JNK2 |
| JNK Inhibitor VIII | JNK | |
| Wee1 Inhibitor | 681640, Wee1 Inhibitor | WEE1, CHEK1 |
| Nutlin-3a (-) | MDM2 | |
| Mirin | MRE11 | |
| PD173074 | PD-173074, PD 173074 | FGFR1, FGFR2, FGFR3 |
| ZM447439 | ZM-447439, ZM 447439 | AURKA, AURKB |
| Alisertib | MLN8237 | AURKA |
| RO-3306 | CDK1 | |
| MK-2206 | MK 2206, MK2206 | AKT1, AKT2 |
| Palbociclib | PD0332991, PD-0332991, PF-00080665-73 | CDK4, CDK6 |
| Dactolisib | NVP-BEZ235, BEZ235 | PI3K (class 1), MTORC1, MTORC2 |
| Pictilisib | GDC-0941, GDC0941, RG-7621 | PI3K (class 1) |
| AZD8055 | AZD-8055 | MTORC1, MTORC2 |
| PD0325901 | PD-0325901, PD 0325901 | MEK1, MEK2 |
| SB590885 | SB-590885 | BRAF |
| Selumetinib | SN1103949345, AZD1480 | MEK1, MEK2 |
| CCT007093 | PPM1D | |
| Obatoclax Mesylate | GX15-070MS, Obatoclax, GX15-070 | BCL2, BCL-XL, BCL-W, MCL1 |
| EHT-1864 | EHT 1864 | RAC1, RAC2, RAC3 |
| Avagacestat | BMS-708163, BMS 708163 | Amyloid beta20, Amyloid beta40 |
| 5-Fluorouracil | 5-FU | Antimetabolite (DNA & RNA) |
| Dasatinib | BMS-354825-03, BMS-354825, Sprycel | ABL, SRC, Ephrins, PDGFR, KIT |
| Paclitaxel | BMS-181339-01, Taxol, Onxol, Paxene, Praxel, Abraxane | Microtubule stabiliser |
| Crizotinib | Xalkori, PF2341066, PF-2341066, PF 2341066 | MET, ALK, ROS1 |
| Rapamycin | AY-22989, Sirolimus, WY-090217, Torisel, Rapamune | MTORC1 |
| Sorafenib | Nexavar, 284461-73-0, BAY 43-9006 | PDGFR, KIT, VEGFR, RAF |
| BI-2536 | PLK1, PLK2, PLK3 | |
| Irinotecan | Camptosar, (+)-Irinotecan, Irinotecanum, irinotecan hydrochloride | TOP1 |
| Oxaliplatin | DNA alkylating agent | |
| BMS-536924 | BMS 536924 | IGF1R, IR |
| GSK1904529A | GSK-1904529A, GSK 1904529A | IGF1R, IR |
| Tozasertib | MK 0457,MK-0457,MK-045, VX-680 VX 680 VX-68 | AURKA, AURKB, AURKC, others |
| PF-4708671 | PF 4708671, PF4708671 | S6K1 |
| PRIMA-1MET | Prima 1MET, APR-246 | TP53 activation |
| Serdemetan | JNJ-26854165 | MDM2 |
| TW 37 | TW37, TW-37 | BCL2, BCL-XL, MCL1 |
| Erlotinib | Tarceva, RG-1415, CP-358774, OSI-774, Ro-508231, R-1415 | EGFR |
| CCT-018159 | CCT018159, CCT 018159 | HSP90 |
| Rucaparib | PF-01367338, AG-014699, AG-14447, AG-14699 | PARP1, PARP2 |
| Niraparib | MK-4827, MK4827 | PARP1, PARP2 |
| MK-1775 | AZD1775, Adavosertib | WEE1, PLK1 |
| Dinaciclib | SCH727965, SCH 727965, SCH-727-965, MK-7965 | CDK1, CDK2, CDK5, CDK9 |
| Gemcitabine | Gemzar, LY-188011 | Pyrimidine antimetabolite |
| Bortezomib | PS-341, LDP-341, Velcade | Proteasome |
| GSK269962A | GSK 269962A | ROCK1, ROCK2 |
| SB505124 | SB 505124, SB505124 | TGFBR1, ACVR1B, ACVR1C |
| Tamoxifen | Nolvadex, Soltamox, Zynoplex, ICI-46474, Kessar | ESR1 |
| Fulvestrant | ESR | |
| EPZ004777 | EPZ-004777 | DOT1L |
| YK-4-279 | YK 4-279 | RNA helicase A |
| Piperlongumine | Piplartine | Induces reactive oxygen species |
| Daporinad | APO866, FK866, FK866 | NAMPT |
| BMS-345541 | IKK-1, IKK-2 | |
| AZ960 | AZ 960, AZ-960 | JAK2, JAK3 |
| Talazoparib | BMN-673, BMN 973 | PARP1, PARP2 |
| XAV939 | NVP-XAV939, XAV-939, XAV 939 | TNKS1, TNKS2 |
| Trametinib | GSK1120212, Mekinist | MEK1, MEK2 |
| Dabrafenib | GSK2118436, Tafinlar | BRAF |
| Temozolomide | Temodar, Temodal, M-39831, SCH 52365 | DNA alkylating agent |
| Bleomycin (50 uM) | dsDNA break induction | |
| AZD5438 | SN1057898678 | CDK2 |
| IAP_5620 | SN1043546339 | IAP |
| AZD2014 | SN1103949359 | mTORC1, mTORC2 |
| AZD1208 | SN1028350371 | PIM1, PIM2, PIM3 |
| AZD1332 | SN1061387896 | NTRK1, NTRK2, NTRK3 |
| SN-38 | 7-Ethyl-10-Hydroxy-Camptothecin, SN 38 | TOP1 |
| Bicalutamide | ICI-176334, Casodex, Cosudex, ICI 176334 | AR |
| Ruxolitinib | INCB-18424, Ruxolitinib Phosphate, Jakafi | JAK1, JAK2 |
| Linsitinib | OSI-906, ASP-7487 | IGF1R |
| Epirubicin | Ellence, Farmorubicin, IMI-28 | Anthracycline |
| Cyclophosphamide | Cytoxan, Neosar, Cyclophosphamid, Procytox, Cyclophosphane | Alkylating agent |
| Pevonedistat | MLN4924, MLN 4924, MLN-4924 | NAE |
| Sapitinib | AZD8931 | EGFR, ERBB2, ERBB3 |
| Uprosertib | GSK2141795, GSK2141795C, GSK-2141795 | AKT1, AKT2, AKT3 |
| LCL161 | XIAP, IAP1, IAP2 | |
| Lapatinib | Tykerb, Tyverb | EGFR, ERBB2 |
| Luminespib | AUY922, VER-52296,NVP-AUY922, AUY | HSP90 |
| Alpelisib | BYL719, BYL-719, NVP-BYL719 | PI3Kalpha |
| Taselisib | GDC-0032, GDC0032, RG7604 | PI3K (beta sparing) |
| EPZ5676 | EPZ-5676, Pinometostat | DOT1L |
| SCH772984 | CS-1421 | ERK1, ERK2 |
| IWP-2 | Wnt Inhibitor IWP-2 | PORCN |
| Leflunomide | Sulol, SU-101, HWA-486, Arava | Pyrimidine synthesis inhibitor |
| GSK2801 | 1-(7-(2-methylsulfonyl-phenyl)-4-propoxy-1-aza-bicyclo[4.3.0]nona-2,4,6,8-tetraen-9-yl)-ethanone | |
| Bromosporine | ethyl N-[6-(3-methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate | CECR2, BRD2, BRD4, BRD9 |
| SGC-CBP30 | 8-(3-chloro-4-methoxy-phenethyl)-4-(3,5-dimethyl-isoxazol-4-yl)-9-(2-(morpholin-4-yl)-propyl)-7,9-diaza-bicyclo[4.3.0]nona-1(6),2,4,7-tetraene | EP300, CBP |
| GSK-LSD1 | N-((1R,2S)-2-phenylcyclopropyl)piperidin-4-amine | KDM1 |
| BDOCA000347a | 4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methylbenzenesulfonamide | BRPF1, BRPF2, BRPF3 |
| BDF00022089a | BRPF1, BRPF2, BRPF3 | |
| BDILV000379a | 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-4,5-dihydro-1H-imidazol-5-yl)benzonitrile | BAZ2A, BAZ2B |
| Entinostat | MS-275 | HDAC1, HDAC3 |
| OSI-027 | A-1065-5 | MTORC1, MTORC2 |
| LGK974 | LGK-974 | PORCN |
| VE-822 | VE 822, VE822, Berzosertib | ATR |
| WZ4003 | WZ 4003 | NUAK1, NUAK2 |
| CZC24832 | GTPL6653 | PI3Kgamma |
| AZD5582 | GTPL7710, AOB5560 | XIAP, cIAP |
| GSK2606414 | AK175551 | PERK |
| PFI3 | PFI-3, PFI 3, AOB2221 | Polybromo 1, SMARCA4, SMARCA2 |
| PCI-34051 | AK298746 | HDAC8, HDAC6, HDAC1 |
| Wnt-C59 | AOB3540, AK161197 | PORCN |
| I-BET-762 | GSK525762A | BRD2, BRD3, BRD4 |
| RVX-208 | 1044870-39-4, Apabetalone | BRD4 |
| OTX015 | Birabresib, OTX-015, MK-8628 | BRD2, BRD3, BRD4 |
| GSK343 | EZH2 | |
| ML323 | GTPL7898, AOB2313, | USP1, UAF1 |
| Entospletinib | GS-9973 | SYK |
| PRT062607 | P505-15, PRT-2607, BIIB-057 | SYK |
| Ribociclib | LEE011, NVP-LEE011, LEE011-BBA | CDK4, CDK6 |
| AGI-6780 | AK162157 | IDH2 R140Q mutant |
| Picolinici-acid | Picolinate | Inflammatory related |
| AZD5153 | SN1045566955, AZD5153 | BRD4 |
| CDK9_5576 | SN1047226266, CDK9_5576 | CDK9 |
| CDK9_5038 | SN1047483750, CDK9_5038 | CDK9 |
| Eg5_9814 | SN1047613775, Eg5_9814 | KSP11 |
| ERK_2440 | SN1051032892, ERK_2440 | ERK1,ERK2 |
| ERK_6604 | SN1047587618, ERK_6604 | ERK1,ERK2 |
| IRAK4_4710 | SN1050852374, IRAK4_4710 | IRAK4 |
| JAK1_8709 | SN1049200060, JAK1_8709 | JAK1 |
| AZD5991 | SN1049446612, AZD5991 | MCL1 |
| PAK_5339 | SN1046290829, PAK_5339 | PAK1, PAK2 |
| TAF1_5496 | SN1050393042, TAF1_5496 | TAF1 |
| ULK1_4989 | SN1049257073, ULK1_4989 | ULK1 |
| VSP34_8731 | SN1049998399, VSP34_8731 | VSP34 |
| IGF1R_3801 | SN1051640224, IGF1R_3801 | IGFR1 |
| JAK_8517 | SN1066590414, JAK_8517 | JAK1, JAK2 |
| GSK2256098C | FAK1 | |
| GSK2276186C | JAK1, JAK2, JAK3 | |
| GSK2110183B | AKT1, AKT2, AKT3 | |
| GSK626616AC | DYRK1A | |
| GSK3337463A | NIK | |
| GSK2830371A | PPM1D | |
| LMB_AB1 | ADRA1A, ADRB1 | |
| LMB_AB2 | GADD34 | |
| LMB_AB3 | PPP1R15B | |
| AZD4547 | 1035270-39-3 | FGFR1, FGFR2, FGFR3 |
| Ibrutinib | PCI-32765, CRA-032765, PCI-32765-00 | BTK |
| Zoledronate | Zoledronic acid, Zometa, Reclast | |
| Acetalax | Oxyphenisatin acetate | |
| Carmustine | ||
| Topotecan | TOP1 | |
| Teniposide | Vumon | |
| Mitoxantrone | TOP2 | |
| Dactinomycin | Actinomycin D, Cosmegen, Lyovac, Meractinomycin, Ac-De, ActD | RNA polymerase |
| Bleomycin | dsDNA break induction | |
| Fludarabine | Fludara | Antimetabolite |
| Nelarabine | Atriance, Arranon | |
| Dacarbazine | DTIC | CP11A |
| Romidepsin | Istodax, FK228, Depsipeptide | HDAC1, HDAC2, HDAC3, HDAC8 |
| Vincristine | ||
| 123829 | ||
| 765771 | ||
| 123138 | ||
| Podophyllotoxin bromide | ||
| 50869 | ||
| Dihydrorotenone | ||
| 720427 | ||
| 667880 | ||
| Gallibiscoquinazole | ||
| L-Oxonoreleagnine | ||
| 729189 | ||
| 741909 | ||
| 743380 | ||
| Elephantin | ||
| 150412 | ||
| Sinularin | ||
| 615590 | ||
| 630600 | ||
| LMP744 | MJ-III-65 | TOP1 |
| 776928 | ||
| Schweinfurthin A | ||
| BEN | ||
| Sabutoclax | BI-97C1 | BCL2, BCL-XL, BFL1, MCL1 |
| LY2109761 | 5XE | TGFB1 |
| OF-1 | BRPF1B, BRPF2 | |
| MN-64 | TNKS1, TNKS2 | |
| KRAS (G12C) Inhibitor-12 | GTPL8020 | KRAS (G12C) |
| MG-132 | LLL cpd, MG 132, MG132 | Proteasome, CAPN1 |
| BDP-00009066 | MRCKB_HUMAN | |
| Buparlisib | BKM120, NVP-BKM120 | PI3Kalpha, PI3Kdelta, PI3Kbeta, PI3Kgamma |
| Ulixertinib | BVD-523, VRT752271 | ERK1, ERK2 |
| Venetoclax | ABT-199, Veneclexta, GDC-0199 | BCL2 |
| ABT737 | BCL2, BCL-XL, BCL-W, BCL-B, BFL1 | |
| Afuresertib | GSK2110183, GSK2110183C | AKT1, AKT2, AKT3 |
| AGI-5198 | IDH-C35 | IDH1 (R132H) |
| AZD3759 | EGFR | |
| AZD5363 | AKT1, AKT2, AKT3, ROCK2 | |
| AZD6738 | AZD 6738, AZD-6738 | ATR |
| AZD8186 | AZD 8186, AZD-8186 | PI3Kalpha, PI3Kbeta |
| Osimertinib | AZD9291, AZD 9291, AZD-9291, Tagrisso, Mereletinib | EGFR |
| Cediranib | AZD2171, AZD 2171, AZD-2171, Recentin | VEGFR, FLT1, FLT2, FLT3, FLT4, KIT, PDGFRB |
| Ipatasertib | GDC0068, GDC 0068, GDC-0068 | AKT1, AKT, AKT3 |
| GDC0810 | GDC-0810, GDC 0810 | ESR1, ESR2 |
| GNE-317 | GNE317, GNE 317 | PI3Kalpha |
| GSK2578215A | GSK 2578215A, GSK-2578215A | LRRK2 |
| I-BRD9 | GSK602, GSK 602, GSK-602 | BRD9 |
| Telomerase Inhibitor IX | MST-312, MST 312, MST312 | Telomerase |
| MIRA-1 | MIRA 1, MIRA1, NSC19630, NSC-19630, NSC 19630 | TP53 |
| NVP-ADW742 | NVP ADW742, NVPADW742 | IGF1R |
| P22077 | P 22077, P-22077 | USP7, USP47 |
| Savolitinib | AZD6094, Volitinib, AZD-6094, AZD 6094 | MET |
| UMI-77 | UMI 77, UMI-77 | MCL1 |
| WIKI4 | WIKI-4, WIKI 4 | TNKS1, TNKS2 |
| Sepantronium bromide | YM155, YM-155, YM 155 | BIRC5 |
| MIM1 | MIM 1, MIM-1 | MCL1 |
| WEHI-539 | WEHI539, WEHI-539 | BCL-XL |
| BPD-00008900 | ||
| N25720-51-A1 | ||
| N27922-53-1 | ||
| N30652-18-1 | ||
| N29087-69-1 | ||
| HKMTI-1-005 | ||
| ICL-SIRT078 | SIR2 | |
| UNC0638 | G9A, GLP | |
| AGK2 | BAZ2A, BAZ2B | |
| Foretinib | GSK1363089, XL-880, EXEL-2880, GSK089 | MET, KDR, TIE2, VEGFR3/FLT4, RON, PDGFR, FGFR1, EGFR |
| BIBR-1532 | TERT | |
| Pyridostatin | G-quadruplex stabiliser | |
| AMG-319 | AMG319 | PI3K (beta sparing) |
| MK-8776 | SCH900776 | CHEK1, CHEK2, CDK2 |
| Vinorelbine | vinorelbine tartrate, Navelbine, Exelbine | Microtubule destabiliser |
| Mycophenolic acid | ||
| Remodelin | ||
| VX-11e | VX11e, VX11e | ERK2 |
| LJI308 | RSK2, RSK1, RSK3 | |
| AZ6102 | TNKS1, TNKS2 | |
| GSK591 | EPZ015866, GSK3203591 | PMRT5 |
| VE821 | VE 821, VE-821 | ATR |
| VTP-A | ||
| VTP-B | ||
| PBD-288 | ||
| POMHEX | ||
| CT7033-2 | KDM4A, KDM4C, KDM4E, KDM3A, KDM6B | |
| GSK-LSD1-2HCl | LSD1 | |
| 5-azacytidine | DNA methyltransferases | |
| A-366 | EHMT1, EHMT2 | |
| CPI-637 | EP300 | |
| UNC0379 | SETD8 | |
| AZD6482 | AZD 6482, AZD-6482, AK-55409 | PI3Kbeta |
| AT13148 | AKT1 | |
| BMS-754807 | BMS-754807 | IGF1R, IR |
| JQ1 | JQ-1, (+)-JQ-1 | BRD2, BRD3, BRD4, BRDT |
| PFI-1 | BRD4 | |
| IOX2 | IOX-2, IOX 2, AK176060 | EGLN1 |
| CHIR-99021 | CT 99021, CHIR99021, CHIR 99021 | GSK3A, GSK3B |
| SGC0946 | DOT1L | |
| GSK2830371 | None | WIP1 |
| THR-101 | WIMM synthesis | Mutant RAS |
| THR-102 | WIMM synthesis | Mutant RAS |
| THR-103 | WIMM synthesis | Mutant RAS |
| ascorbate (vitamin C) | back-up solution from YWKim | anti-oxidant proteins |
| glutathione | G6013, sigma | anti-oxidant proteins |
| alpha-lipoic acid | aLA | Metabolism |
| N-acetyl cysteine | NAC | Metabolism |
| 5-Azacytidine | DNA alkyltransferase inhibitor | |
| Geldanamycin | Hsp90 inhibitor | |
| Sirolimus | mTOR inhibitor |